反应详情

温度

0 °C

11.1 g of pyridinium chlorochromate and 12 g of celite were suspended in 100 ml of dry dichloromethane, and 6 g of (Z)-4-benzyloxy-2-buten-1-ol was added thereto under stirring at 0° C. The mixture was stirred at room temperature for three hours, and then diethyl ether was added thereto. The insolubles were removed by filtration. The filtrate was subjected to distillation under reduced pressure for removal of the solvent, and the residue was purified by silica gel column chromatography (diethyl ether) to obtain 3.9 g of (Z)-4-benzyloxy-butenal as slightly yellow oily substance.

1. stirringThe mixture was stirred at room temperature for three hours
2. customThe insolubles were removed by filtration
3. distillationThe filtrate was subjected to distillation under reduced pressure for removal of the solvent
4. customthe residue was purified by silica gel column chromatography (diethyl ether)