HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 19096887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,4-Difluoroaniline | HCID 9709 | — |
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 1-(Ethoxycarbonyl)cyclopropanecarboxylic acid | HCID 11789472 | — |
| Product | HCID 19096887 | HCID 19096887 | 75% |
Reaction Steps
1-Carboethoxycyclopropanecarboxylic acid 7.00 grams, 0.04 mole), ethyl chloroformate (4.8) grams, 0.04 mole) and 2.4-difluoroaniline (5.72 grams, 0.04 mole) were reacted sequentially in the presence of triethylamine (4.51 grams, 0.04 mole) in a manner similar to that described in Example XXXIII to give 7.13 grams (0.03 mole) of ethyl 1-(2,4-difluorophenylaminocarbonyl)cyclopropanecarboxylate as a white crystalline solid having a melting point of 79° C.-80.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05123951 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-54087aee5e744abb806995f33b0349dc |
| Source note | uspto-grants-1992_06 |