Water → HCID 23675715, compound

Participants

Reaction Steps

n-Propyl 3-[(3,5-dichlorophenyl)amino]-2-methoxy-3-oxopropanoate (5.47 grams, 0.02 mole), prepared in Example LXXI (Compound 234) was saponified with potassium hydroxide (1.01 grams, 0.02 mole) in the presence of 75 milliliters of ethanol and 0.31 gram (0.02 mole) of water in a manner similar to that described in Example LXXI Part B. The potassium salt that separated from the reaction mixture was filtered off, washed with ethanol and dried to give 0.98 gram (0.003 mole) of potassium 3-[(3,5-dichlorophenyl)amino]-2-methoxy-3-oxopropanoate. NMR analysis of the product indicated the following:

Provenance & Evidence