4-Hydroxybenzoic Acid → (2R,5R)-2-(4'-pentyloxycarbonylphenoxy)-5-hexyl-delta-valerolactone

Participants

Reaction Steps

A crude product was obtained in the same manner as described in Example 22 except that (2S,5R)-2-hydroxy-5-hexyl-δ-valerolactone was used in an amount of 125 mg and 125 mg of p-hydroxybenzoic acid was used instead of 120 mg of 4-octyloxy-3-cyanobenzoic acid. The crude product was purified by the silica gel column chromatography to obtain 20 mg of (2R,5R)-2-(4'-pentyloxycarbonylphenoxy)-5-hexyl-δ-valerolactone.

Provenance & Evidence