Ethyl chloroformate → HCID 19891922, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 4-chloro-2-(4-methoxybenzylthio)-N,N-dimethylbenzylamine (D19) (2.49 g, 7.7 mmol) in dry toluene (80 ml) was cooled in ice whilst ethyl chloroformate (0.9 ml, 9.4 mmol) was added dropwise. A solid slowly separated, and after 1 h at 0-5° C. the mixture was heated under reflux for 2 h. The solvent was removed in vacuo, then the residue was repeatedly dissolved in toluene and evaporated to dryness (3 times) to give the title compound as a light brown oil (2.36 g, 98%).

Provenance & Evidence