HCID 131717433, compound → HCID 131717432, compound

HRID 893297Notes

Reaction equation

HRID 893297 reaction equation
[Cl:1][C:2]1[C:3]([S:31]CC2C=CC(OC)=CC=2)=[C:4]([C:8]([CH2:27][CH:28]([CH3:30])[CH3:29])([CH3:26])[C:9]([NH:11][CH:12]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][NH:14][C:13]2=[O:25])=[O:10])[CH:5]=[CH:6][CH:7]=1>CCCCCC>[Cl:1][C:2]1[C:3]([SH:31])=[C:4]([C:8]([CH2:27][CH:28]([CH3:29])[CH3:30])([CH3:26])[C:9]([NH:11][CH:12]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][NH:14][C:13]2=[O:25])=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 131717433HCID 131717433, compound

Product 1

HCID 131717432HCID 131717432, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

The title compound was prepared as a 1:1 mixture of diastereoisomers from 3-chloro-2-(4-methoxybenzylthio)-α-(2-methylpropyl)-N-(2-oxo-3-azacylotridecyl)phenylpropanamide in a similar manner to that described in Example 4, mp 143°-148° C. (after trituration with hexane).

Sources & evidence

ORD record
ord-0c0e4067adfd47879bfd05afdcebb93b
Source dataset
uspto-grants-1992_06
Patent number
US05124322

Reaction notes

Loading…