HuagongsheHuagongshe Chemistry Print Report · For research reference only
Styrene Oxide → T6668830
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Styrene Oxide | HCID 7276 | — |
| Reactant | Veratrylamine | HCID 79832 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | T6668830 | HCID 4719987 | 46.7% |
Reaction Steps
Heat a solution of 3,4-dimethoxybenzylamine (16.7 g) and styrene oxide (12.0 g) in acetonitrile (250 mL) at reflux for 16 h. Concentrate to a residue and distill the residue, collecting the fraction distilling above 120° C. (0.5 mm). Recrystallize the solidified distillate from benzene/hexane to give N-(3,4-dimethoxybenzyl)-2-hydroxy-2-phenylethylamine (13.4 g), mp=93°-94° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05124337 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-ab45bb94c8cc49eb9720fccebb2167fb |
| Source note | uspto-grants-1992_06 |