Chloro(phenyl)acetyl chloride → HCID 19892256, compound
Reaction equation
[C:1]([NH2:8])(=[S:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].Cl[CH:10]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:11](Cl)=[O:12]>>[CH2:2]([C:1]1[S:7][C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:11]([OH:12])[N:8]=1)[CH2:3][CH2:4][CH2:5][CH3:6]Participants
3
Procedure
The title compound was prepared according to the method of Scheme II in a manner analogous to Example 31 except thiohexanamide was used instead of thiobenzamide and 2-chloro-2-phenylacetyl chloride was used instead of 2-bromopropionate.
Sources & evidence
- ORD record
- ord-f1a1f3aa99e745b58fd71189589dddcd
- Source dataset
- uspto-grants-1992_06
- Patent number
- US05124342
Reaction notes
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