HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 2-Propyl-1H-pyrrolo[2,3-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-(Phenylsulfonyl)-2-propyl-1H-pyrrolo[2,3-b]pyridine | HCID 19892205 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Propyl-1H-pyrrolo[2,3-b]pyridine | HCID 18946710 | — |
Reaction Steps
A mixture of 1-(benzenesulfonyl)-2-propyl-1H-pyrrolo[2,3-b]pyridine (67 mg) and KOH (200 mg) in MeOH (30 mL) was heated to reflux for 3 h. The mixture was concentrated, neutralized by addition of 1N HCl, extracted (EtOAc) and purified (SiO2, 25% EtOAc/hexane) to give 2-propyl-1H-pyrrolo-[2,3-b]pyridine as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05124335 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-98d7a0621934468da4aa39e8bb3eb98e |
| Source note | uspto-grants-1992_06 |