Dichloromethane → HCID 178438385, compound

Participants

Reaction Steps

To a stirred solution of 4-methyl-2-propyl-1-[[2'-(1-triphenylmethyl-1H-tetrazol-5-yl)[1,1']-biphenyl-4-yl]methyl]-1H-pyrrolo[2,3-b]pyridine (68 mg, 0.11 mmol) in 30 mL of 2:1 MeOH--CH2Cl2 at rt was added 2 drops of conc HCl. After 30 min 3 drops of conc NH4OH were added. Concentration and purification by flash chromatography (SiO2, 25% EtOAc/hexanes) gave 2-propyl-1-[[2'-(1H-tetrazol-5-yl)-[1,1']-biphenyl-4-yl]methyl]-1H-pyrrolo[2,3-b]-pyridine as a solid. FAB MS M+ +1=395.

Provenance & Evidence