HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(2,4-dimethoxyphenyl)prop-2-enoate → 3-(2,4-Dimethoxyphenyl)propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(2,4-dimethoxyphenyl)prop-2-enoate | HCID 54162205 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(2,4-Dimethoxyphenyl)propionic acid methyl ester | HCID 14521158 | — |
Reaction Steps
113.8 g of methyl 2,4-dimethoxycinnamate are dissolved in 1.5 1 of methanol while heating and are hydrogenated on 5 g of catalyst (10% Pd/C). The catalyst is removed by filtration and the filtrate is concentrated. 113 g of an oil remain and are immediately used in the subsequent Friedel-Crafts acylation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05124478 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-ec4adbdfa28e41358ef389642fef436c |
| Source note | uspto-grants-1992_06 |