Ethyl acetate hexane → HCID 22399579, compound

HRID 893479Notes

Reaction equation

HRID 893479 reaction equation
[NH2:1][C:2]([C:4]1[CH:31]=[CH:30][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:26]=[CH:25][C:16]3[CH:17]=[CH:18][CH:19]([C:21]([O:23][CH3:24])=[O:22])[O:20][C:15]=3[C:14]=2[CH2:27][CH2:28][CH3:29])=[C:6]([CH2:32][CH:33]2[CH2:35][CH2:34]2)[C:5]=1[OH:36])=[O:3].[C:37](OCC)(=O)C.CCCCCC>>[NH2:1][C:2]([C:4]1[CH:31]=[CH:30][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:26]=[CH:25][C:16]3[CH:17]=[CH:18][CH:19]([C:21]([O:23][CH3:24])=[O:22])[O:20][C:15]=3[C:14]=2[CH2:27][CH2:28][CH3:29])=[C:6]([CH2:32][CH:33]2[CH2:35][CH2:34]2)[C:5]=1[O:36][CH3:37])=[O:3]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 22399592HCID 22399592, compound

Product 1

HCID 22399579HCID 22399579, compound

Procedure

The compound of Example 67 is exposed to the conditions described in Example 25. Chromatography of the crude product on silica gel using ethyl acetate/hexane, (3:7) as eluant affords the product.

Workup

  1. customaffords the product

Sources & evidence

ORD record
ord-8af94505189d4d0ea28057aec8a7fceb
Source dataset
uspto-grants-1992_06
Patent number
US05124350

Reaction notes

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