HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 19890445, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 19890444 | HCID 19890444 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19890445 | HCID 19890445 | 55% |
Reaction Steps
5-Benzyloxy 6-butoxy indole (0.5 g, 0.0017 mole) is hydrogenated under 50 atmospheres of hydrogen in a reactor with 5 ml of absolute ethanol and 70 mg of 10% palladium on carbon for 2 hours. After filtration and evaporation of the solvent, the residue is purified by chromatography on silica 60 (eluent: CH2Cl2, to obtain 6-butoxy 5-hydroxy indole (0.19 g, beige powder, yield 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05126125 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-b56e569473484bb3aac99a2a5221cbda |
| Source note | uspto-grants-1992_06 |