N,N-Dimethylbenzylamine → N-Benzyl-N,N-dimethyl-2-phenoxyethan-1-aminium bromide

Participants

Reaction Steps

A solution of 40.21 grams (0.20 mol) of 2-bromoethyl phenyl ether, 27.04 grams (0.20 mol) of N,N-dimethylbenzylamine and 135 milliters of acetonitrile was heated at reflux for 16.75 hrs. The reaction mixture was concentrated and then cooled. On standing, the residue crystallized. The solid was stirred in ether, collected and dried. The yield of product was 66.0 grams (98.13% of theory); mp=100°-110° C.

Provenance & Evidence