Sodium Carbonate → HCID 15101024, compound

HRID 893653Notes

Reaction equation

HRID 893653 reaction equation
Cl[CH2:2][C:3]([N:5]1[CH2:10][CH:9]=[C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:7]2[N:17]=[CH:18][C:19]([C:20]#[N:21])=[C:6]12)=[O:4].[CH2:22]([N:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.C(=O)([O-])[O-].[Na+].[Na+]>C1(C)C=CC=CC=1>[C:11]1([C:8]2[N:7]3[N:17]=[CH:18][C:19]([C:20]#[N:21])=[C:6]3[N:5]([C:3](=[O:4])[CH2:2][N:32]3[CH2:33][CH2:34][N:29]([CH2:22][C:23]4[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=4)[CH2:30][CH2:31]3)[CH2:10][CH:9]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 759941-BenzylpiperazineHCID 19756218HCID 19756218, compound

Product 1

HCID 15101024HCID 15101024, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 3.8 g of 4-(chloroacetyl)-4,5-dihydro-7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile, 2.5 ml of N-benzylpiperazine and 1.6 g of sodium carbonate in 165 ml of toluene was reacted as described in Example 146, giving 4 g of the desired product, mp 156-158.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-4886df0c455d449a82e2fa288c6475d6
Source dataset
uspto-grants-1992_06
Patent number
US05126340

Reaction notes

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