HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 893799Generated: October 30, 2026
Potassium Carbonate → HCID 178496815, compound
https://huagongshe.com/reaction/893799
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,4,6-Trichloropyrimidine | HCID 77378 | — |
| Reactant | Carbamimidic acid, methyl ester, sulfate (1:1) | HCID 169039 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 178496815 | HCID 178496815 | 142.6% |
Reaction Steps
45.9 g (0.25 mol) of 2,4,6-trichloropyrimidine, 30.8 g (0.125 mol) of O-methyl-isourea sulphate and 51.8 g (0.375 mol) of ground potassium carbonate are suspended in 800 ml of toluene and stirred at 110° C. for 10 hours. After cooling, the crystalline solid is filtered off with suction, stirred with water for 15 minutes and again filtered off with suction. 39.4 g of N-(4,6-dichloro-pyrimidin-2-yl)-O-methylisourea are obtained (GC purity 98%: 38.6 g; yield: 69 of theory), melting point 178° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05126454 |
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| Source dataset | uspto-grants-1992_06 |
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| ORD ID | ord-9a30900b756348de8722cd5a26d78ae1 |
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| Source note | uspto-grants-1992_06 |
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