2,6-Diisopropylphenyl isocyanate → HCID 19891420, compound

HRID 893809Notes

Reaction equation

HRID 893809 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:9][NH2:10])[CH:5]=[CH:6][CH:7]=1.[CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:26])[CH3:25])[C:19]=1[N:27]=[C:28]=[O:29])([CH3:17])[CH3:16]>CCCCCC>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:9][NH:10][C:28]([NH:27][C:19]2[C:18]([CH:15]([CH3:16])[CH3:17])=[CH:23][CH:22]=[CH:21][C:20]=2[CH:24]([CH3:26])[CH3:25])=[O:29])[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 19891422HCID 19891422, compound

Product 1

HCID 19891420HCID 19891420, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent2×

Procedure

To 20 ml of n-hexane was added 1.81 g (9.5 mmol) of 2-(3-methylphenyl)hexylamine. An 18 ml of 0.52M hexane solution of 2,6-diisopropylphenyl isocyanate was added dropwise to the mixture under ice cooling. The resulting mixture was stirred overnight and the precipitated crystals were collected by filtration to give 1.87 g (50% yield) of 1-(2-(3-methylphenyl)hexyl)-3-(2,6-diisopropylphenyl)urea.

Workup

  1. filtrationthe precipitated crystals were collected by filtration

Sources & evidence

ORD record
ord-8c3e30f7d8e746c9a435b75a9a53ca25
Source dataset
uspto-grants-1992_06
Patent number
US05126483

Reaction notes

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