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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 893826Generated: October 25, 2026

Benzonitrile, 4-(trifluoromethyl)- → 4-Methylbenzotrifluoride

https://huagongshe.com/reaction/893826

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, 4-(trifluoromethyl)-HCID 67995—
SolventMethanolHCID 887—
Product4-MethylbenzotrifluorideHCID 8023091%

Reaction Steps

To 4 ml of methanol (3.06 g) was added 0.71 g of p-trifluoromethylbenzonitrile. The solution was added to the reactor at 0.34 ml/min. The product, p-trifluoromethyltoluene, was isolated in a methanol solution in a 91% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05126497
Source datasetuspto-grants-1992_06
ORD IDord-84acf6a8785148ce8de82354af2abfe6
Source noteuspto-grants-1992_06