Benzyl Bromide → HCID 14423288, compound

Participants

Reaction Steps

React 10-(3-chlorophenyl)-6,7,8,9-tetrahydropyrido[2,3-b] [1,6]naphthyridin-5(10H)-one (5 mmol) with benzylbromide (5.8 mmol) in acetone (40 ml) at 25° C. for 3 hours. Evaporate the acetone solvent, and elute the product from silica gel with chloroform to provide the product, 10-(3-chlorophenyl)-6,7,8,9-tetrahydro-7-N-benzyl-pyrido[2,3-b] [1,6]naphthyridin-5(10H)-one, m.p. 157°-161° C. after crystallization from CH3CN.

Provenance & Evidence