HCID 14423248, compound → HCID 14423299, compound

Participants

Reaction Steps

Reflux a mixture of 4-(3-chlorophenyl)-2,3-dihydrothieno[3,2-b] [1,8]naphthyridin-9(9H)-one (0.11 g), ethanol (100 ml), and commercial aged Raney nickel (from 5 ml of an aqueous suspension) for 10 hours under nitrogen. Filter the resulting mixture, evaporate the solvent, and chromatograph the residue over silica gel. Elute with CHCl3 to give 4-(3-chlorophenyl)-thieno[3,2-b] [1,8]naphthyridin-9(4H)-one, m.p. 264°-267° C. from CHCl3 hexane.

Provenance & Evidence