HRID893850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7477

Benzoyl chloride, 4-methoxy-

C8H7ClO2

HCID7918

Acetic anhydride

C4H6O3

HCID69110

Benzoyl chloride, 2-chloro-

C7H4Cl2O

HCID19960928

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1C(C(=O)c2ccc(OC)cc2)SC23C=CC=CC2=NCCC13

HCID69959091

未命名化合物

结构：CCOC(=O)C1C(C(C)=O)SC23C=CC=CC2=NCCC13

HCID69959664

未命名化合物

PROCEDURE

实验过程

2-Acetyl-1,2,3,4-tetrahydro-benzo[b]thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester and 2-(4-methoxybenzoyl)-1,2,3,4-tetrahydro-benzo[b]thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester were synthesized using 1,2,3,4-tetrahydro-benzo[b]thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester as the starting material by following the same procedure as in Example 5 except that 324 mg of acetic anhydride or 510 mg of 4-methoxybenzoyl chloride, respectively, in place of 614 mg of 2-chlorobenzoyl chloride in Example 5.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c82d6f31bd804c8dac44808a15e1856d
来源数据集: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05126448
来源说明: uspto-grants-1992_06

反应 SMILES

[CH2:1]([O:3][C:4]([CH:6]1[CH:14]2[C:9]3([CH:18]=[CH:17][CH:16]=[CH:15][C:10]3=[N:11][CH2:12][CH2:13]2)[S:8][CH2:7]1)=[O:5])[CH3:2].[C:19](OC(=O)C)(=[O:21])[CH3:20].[CH3:26][O:27][C:28]1[CH:36]=[CH:35][C:31]([C:32](Cl)=[O:33])=[CH:30][CH:29]=1.ClC1C=CC=CC=1C(Cl)=O>>[CH2:1]([O:3][C:4]([CH:6]1[CH:14]2[C:9]3([CH:18]=[CH:17][CH:16]=[CH:15][C:10]3=[N:11][CH2:12][CH2:13]2)[S:8][CH:7]1[C:19](=[O:21])[CH3:20])=[O:5])[CH3:2].[CH2:1]([O:3][C:4]([CH:6]1[CH:14]2[C:9]3([CH:18]=[CH:17][CH:16]=[CH:15][C:10]3=[N:11][CH2:12][CH2:13]2)[S:8][CH:7]1[C:32](=[O:33])[C:31]1[CH:35]=[CH:36][C:28]([O:27][CH3:26])=[CH:29][CH:30]=1)=[O:5])[CH3:2]