Potassium Hydroxide → HCID 178474155, compound

HRID 893884Notes

Reaction equation

HRID 893884 reaction equation
F[S:2]([CH2:5][CH2:6][NH:7][C:8]1[CH:13]=[C:12]([NH:14][C:15](=[O:17])[CH3:16])[CH:11]=[CH:10][C:9]=1[CH3:18])(=[O:4])=[O:3].[OH-:19].[K+:20]>O>[K:20][CH:5]([S:2]([OH:19])(=[O:4])=[O:3])[CH2:6][NH:7][C:8]1[CH:13]=[C:12]([NH:14][C:15](=[O:17])[CH3:16])[CH:11]=[CH:10][C:9]=1[CH3:18]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 21161676HCID 21161676, compound

Product 1

HCID 178474155HCID 178474155, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

N-(2-Fluorosulfonylethyl-2-methyl-5-acetamidoaniline (13.7 g, 0.05 m) is stirred with water (100 ml.) and potassium hydroxide (5.0 g) at room temperature for 2 hrs. when thin-layer chromatography shows reaction to be complete. The aqueous solution is used in the coupling reaction without further isolation.

Workup

  1. customreaction
  2. customThe aqueous solution is used in the coupling reaction without further isolation

Sources & evidence

ORD record
ord-5c36bd6f2c1a47e2b51c42c8cfa486c9
Source dataset
uspto-grants-1981_08
Patent number
US04282144

Reaction notes

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