Toluene → HCID 21162018, compound

HRID 893963Notes

Reaction equation

HRID 893963 reaction equation
[C:1]([CH:3]1[CH2:5][NH:4]1)#[N:2].C1(C)C=CC=CC=1.[CH2:13]([C:18]([N:20]=[C:21]=[O:22])=[O:19])[CH2:14][CH2:15][CH2:16][CH3:17]>C(OCC)C>[CH2:13]([C:18]([NH:20][C:21]([N:4]1[CH2:5][CH:3]1[C:1]#[N:2])=[O:22])=[O:19])[CH2:14][CH2:15][CH2:16][CH3:17]

Participants

5

Reactant 3

HCID 1140Toluene2×HCID 118115Aziridine-2-carbonitrileHCID 10877205HCID 10877205, compound

Product 1

HCID 21162018HCID 21162018, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In a manner analogous to that described in Example 14, from 0.81 g. 2-cyanoaziridine, dissolved in 8 ml. toluene, and a solution of 1.7 g. n-pentanecarbonyl isocyanate in 17 ml. toluene, there are obtained, without purification with diethyl ether, 1.6 g. 1-(N-n-pentanecarbonyl-carbamoyl)-1-cyanoaziridine; m.p. 143°-144° C.

Sources & evidence

ORD record
ord-1322fa3678024321af2a4f202f299d31
Source dataset
uspto-grants-1981_08
Patent number
US04282212

Reaction notes

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