HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178434625, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 178434626 | HCID 178434626 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | HCID 178434625 | HCID 178434625 | — |
Reaction Steps
A mixture of 3-methyl-4-nitropyrazole-5-carboxamide (17.0 g, 0.1 mol) in a mixture of 20 ml of 97-100% formic acid, 160 ml of ethanol and 30 ml of water was hydrogenated overnight at 40°-60° using 150 mg of 5% palladium-on-charcoal at 50 psi. Filtration of the hot solution through Celite and evaporation gave 17.8 g of crude, ochre-colored product which was recrystallized from ethanol: 1st crop 9.3 g colorless, 2nd crop 6.7 g brownish, total yield, 16.0 g (95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04282361 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-3bdbab5d1cd244b2a8a602a5924a7946 |
| Source note | uspto-grants-1981_08 |