Carbamimidothioic acid, N-cyano-N'-2-propynyl-, methyl ester → N-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(2-pyridyl)methylthio]ethyl}guanidine

HRID 894132Notes

Reaction equation

HRID 894132 reaction equation
[C:1]([NH:3][C:4](=[N:7][CH2:8][C:9]#[CH:10])SC)#[N:2].[N:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH2:17][S:18][CH2:19][CH2:20][NH2:21]>>[C:1]([NH:3][C:4]([NH:7][CH2:8][C:9]#[CH:10])=[N:21][CH2:20][CH2:19][S:18][CH2:17][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][N:11]=1)#[N:2]

Participants

3

Reactant 2

HCID 2805748Carbamimidothioic acid, N-cyano-N'-2-propynyl-, methyl esterHCID 128894012-((2-Aminoethyl)thiomethyl)pyridine

Product 1

HCID 136023173N-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(2-pyridyl)methylthio]ethyl}guanidine

Procedure

The product of Step A is reacted with about an equimolar amount of 2-[(2-pyridyl)methylthio]ethylamine in a nonreactive solvent to give after workup, the title product.

Workup

  1. customto give after workup

Sources & evidence

ORD record
ord-378f167b2f4546df81300d905ee17196
Source dataset
uspto-grants-1981_08
Patent number
US04282363

Reaction notes

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