HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 2-(3-Chloropyrid-2-ylmethylthio)ethylamine | HCID 12951532 | — |
| Reactant | 3,3-Dimethoxyprop-2-enenitrile | HCID 22622700 | — |
| Reactant | 1-Cyano-2-methoxy-2-[2-((3-chloro-2-pyridyl)methylthio)ethylamino]ethylene | HCID 70572173 | — |
| Product | 1-Cyano-2-(2-propynylamino)-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene | HCID 73683988 | — |
Reaction Steps
When 2-[(3-chloro-2-pyridyl)methylthio]ethylamine is reacted with 1-cyano-2,2-bis(methoxy)ethylene and the resultant 1-cyano-2-methoxy-2-{2-[(3-chloro-2-pyridyl)-methylthio]ethylamino}ethylene is reacted with propargylamine according to the general procedure of Example 1 Step B the title compound is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04282363 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-b938712fb1db43e2a98484f7124e5de0 |
| Source note | uspto-grants-1981_08 |