HCID 20570259, compound → HCID 136038687, compound

HRID 894140Notes

Reaction equation

HRID 894140 reaction equation
[C:1]([NH:3][C:4]([NH:9][CH2:10][C:11]#[CH:12])=[N:5][CH2:6][CH2:7][SH:8])#[N:2].Cl.[CH3:14][N:15]([CH2:17][C:18]1[N:23]=[C:22]([CH2:24]Cl)[CH:21]=[CH:20][CH:19]=1)[CH3:16]>>[C:1]([NH:3][C:4]([NH:9][CH2:10][C:11]#[CH:12])=[N:5][CH2:6][CH2:7][S:8][CH2:24][C:22]1[CH:21]=[CH:20][CH:19]=[C:18]([CH2:17][N:15]([CH3:14])[CH3:16])[N:23]=1)#[N:2]

Participants

3

Reactant 2

HCID 20570259HCID 20570259, compoundHCID 136182246N-Cyano-N'-propargyl-N"-(2-mercaptoethyl)guanidine

Product 1

HCID 136038687HCID 136038687, compound

Procedure

A ethanolic solution of the product of Step A of Example 6 is reacted with about an equimolar amount of 6-dimethylaminomethyl-2-chloromethylpyridine hydrochloride and about three equivalents of base, and the title compound is produced.

Sources & evidence

ORD record
ord-daea3525800146f682cc93ce309dbae9
Source dataset
uspto-grants-1981_08
Patent number
US04282363

Reaction notes

Loading…