反应详情

Add 13.33 gm. (0.0415 mole) of 5-bromo-α-phenoxy-o-toluate to a solution of 3.32 gm. (0.0830 mole) of sodium hydroxide in 23 ml. of water and 200 ml. of methanol and heat at reflux for 1 hour. Remove the methanol under vacuum. Dissolve the residue in 200 ml. of water and acidify with concentrated hydrochloric acid to the Congo Red end point. Remove the solids by filtration and dry to obtain the title product (yield 12.02 gm. m.p. 160°-163° C.).

1. additionAdd 13.33 gm
2. temperatureat reflux for 1 hour
3. customRemove the methanol under vacuum
4. dissolutionDissolve the residue in 200 ml
5. customRemove the solids
6. filtrationby filtration
7. customdry