Acetic Acid → HCID 21162734, compound

Participants

Reaction Steps

Reflux a mixture of 2.8 gm. (0.010 mole) of 6,11-dihydro-3-isopropyl-11-oxodibenz[b.e]oxepin-9-carbonitrile, 50 ml. of acetic acid, 5 ml. of water and 5 ml. of concentrated hydrochloric acid for 140 hours. Cool the reaction mixture, separate the solids by filtration and dry. (yield 2.07 gm., m.p. 202°-204° C.). Recrystallize from toluene to obtain the title product (m.p. 203°-204.5° C.).

Provenance & Evidence