HuagongsheHuagongshe Chemistry Print Report · For research reference only
11-Methylene-6,11-dihydrodibenz[b,e]oxepin-2-carboxylic acid → 11-Methyl-6,11-dihydrodibenz[b,e]oxepin-2-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 11-Methylene-6,11-dihydrodibenz[b,e]oxepin-2-carboxylic acid | HCID 12929133 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 11-Methyl-6,11-dihydrodibenz[b,e]oxepin-2-carboxylic Acid | HCID 12929134 | 70.4% |
Reaction Steps
Dissolve 514 mg of 11-methylene-6,11-dihydrodibenz[b,e]oxepin-2-carboxylic acid in 150 ml. of ethanol. Add 100 mg of 5% palladium on carbon catalyst. Hydrogenate at 20 psi for 30 minutes. Filter and strip the filtrate to dryness. Recrystallize the residue from isopropanol to obtain the title product (yield 365 mg, m.p. 224°-226° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04282365 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-5c4ef8f90bd149b48d2a71d8c3ea4744 |
| Source note | uspto-grants-1981_08 |