참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Hydrazine | HCID 9321 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 5-Benzoylfuran-2-carboxylic acid | HCID 2877255 | — |
| 용매 | Ethylene Glycol | HCID 174 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Benzyl-2-furoic acid | HCID 2832252 | 63.6% |
반응 단계
5-Benzoylfuran-2-carboxylic acid [420 mg.; Knoppova et al. Collect. Czech. Chem. Commun. 42, 3175-9 (1977), Chem. Abs. 88, 169842d] was combined with 10 ml. of hydrazine, 1.5 g. of potassium hydroxide and 10 ml. of ethylene glycol and heated for 1.5 hours in an oil bath maintained at 160° C. The mixture was cooled in an ice-water bath, diluted with water and acidified with conc. hydrochloric acid. Filtration gave 5-benzylfuran-2-carboxylic acid (250 mg., m/e 202).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04282246 |
|---|
| 출처 데이터셋 | uspto-grants-1981_08 |
|---|
| ORD ID | ord-d0b0ed8c215249d0b0cc35f65a543bc0 |
|---|
| 출처 메모 | uspto-grants-1981_08 |
|---|
