Sulfuric Acid → HCID 20532900, compound

HRID 894302Notes

Reaction equation

HRID 894302 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9](C#N)[C:10](=[O:18])[CH2:11][CH2:12][C:13]([O:15]CC)=[O:14].S(=O)(=O)(O)O>C(O)(=O)C.O>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10](=[O:18])[CH2:11][CH2:12][C:13]([OH:15])=[O:14]

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 20532902HCID 20532902, compound

Product 1

HCID 20532900HCID 20532900, compoundYield 46%

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

This acid was prepared by refluxing 106.5 g (0.390 mol) of ethyl 5-(2',4'-dimethylphenyl)-5-cyano-4-ketopentanoate in 350 ml of glacial acetic acid, 122 ml of water, and 122 ml of concentrated sulfuric acid. The procedure is described in Example I, Part B. The product was obtained as a dark-colored viscous oil, 39.2 g (46% yield).

Workup

  1. customThis acid was prepared
  2. customThe product was obtained as a dark-colored viscous oil, 39.2 g (46% yield)

Sources & evidence

ORD record
ord-addb73c4b4874ae89522ceaa13456316
Source dataset
uspto-grants-1981_08
Patent number
US04283348

Reaction notes

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