HCID 12889638, compound → HCID 20575116, compound

HRID 894320Notes

Reaction equation

HRID 894320 reaction equation
[N:1]([CH2:4][CH:5]1[O:9][N:8]=[C:7]([C:10]2[CH:15]=[CH:14][C:13](Cl)=[CH:12][CH:11]=2)[CH2:6]1)=[C:2]=[S:3].N(CC1ON=C([C:26]2[CH:31]=[CH:30][C:29](C(F)(F)F)=[CH:28][CH:27]=2)C1)=C=S.ClC1C=CC=C(Cl)C=1C1CC(CN=[C:51]=[S:52])ON=1.N(CC1[O:61][N:60]=C(C2C=CC(C)=CC=2)C1)=C=S.N(CC1[O:77]N=C(C2C=CC=CN=2)C1)=C=S>>[N:1]([CH2:4][CH:5]1[O:9][N:8]=[C:7]([C:10]2[C:15]([N+:60]([O-:61])=[O:77])=[C:14]([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)[CH:13]=[C:12]([S:52][CH3:51])[CH:11]=2)[CH2:6]1)=[C:2]=[S:3]

Participants

6

Reactant 5

HCID 12889638HCID 12889638, compoundHCID 12889648HCID 12889648, compoundHCID 12889649HCID 12889649, compoundHCID 12889651HCID 12889651, compoundHCID 12889656HCID 12889656, compound

Product 1

HCID 20575116HCID 20575116, compound

Procedure

The preferred compounds are 5-isothiocyanatomethyl-3-(4-chlorophenyl)-2-isoxazoline, 5-isothiocyanatomethyl-3-(4-trifluoromethylphenyl)-2-isoxazoline, 3-(2,6-dichlorophenyl)-5-isothiocyanatomethyl-2-isoxazoline, 5-isothiocyanatomethyl-3-(4-methylphenyl)-2-isoxazoline, and 5-isothiocyanatomethyl-3-(2-pyridyl)-2-isoxazoline.

Sources & evidence

ORD record
ord-1f34ff6098c54dcba23d79ab1fcb7f92
Source dataset
uspto-grants-1981_08
Patent number
US04283403

Reaction notes

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