Allyl Isothiocyanate → 3-(4-Bromophenyl)-5-isothiocyanatomethyl-2-isoxazoline

HRID 894322Notes

Reaction equation

HRID 894322 reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([CH:6]=[N:7][OH:8])=[CH:4][CH:3]=1.[CH2:11]([N:14]=[C:15]=[S:16])[CH:12]=[CH2:13]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]2[CH2:13][CH:12]([CH2:11][N:14]=[C:15]=[S:16])[O:8][N:7]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 5971Allyl Isothiocyanate

HCID 6080884-Bromobenzaldehyde Oxime

Product 1

HCID 128896523-(4-Bromophenyl)-5-isothiocyanatomethyl-2-isoxazoline

Procedure

A 10 g. portion of 4-bromobenzaldoxime was chlorinated and reacted with 10 g. of allylisothiocyanate to prepare 15 g. of product, m.p. 123°-125°.

Workup

customreacted with 10 g

Sources & evidence

ORD record: ord-395a8587d90f41a7a679905ab23922ba
Source dataset: uspto-grants-1981_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04283403

Reaction notes

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