2-Chloro-N,N-dimethylethylamine → HCID 20574346, compound

Participants

Reaction Steps

In a manner analogous to that described in Example 1, 26.6 g. 1-(3-picolyl)-3-hydroxy-4-phenyl-2-pyrrolin-2-one is reacted with 20.0 g. β-dimethylaminoethyl chloride. The base so obtained is converted into the crystalline oxalate in isopropanol and then recrystallized from methanol. There is obtained 20.4 g. (39% of theory) 1-(3-picolyl)-3-(β-dimethylaminoethoxy)-4-phenyl-3-pyrrolin-2-one oxalate; m.p. 160° C. (decomp.).

Provenance & Evidence