HCID 13787828, compound → HCID 12929196, compound

HRID 894521Notes

Reaction equation

HRID 894521 reaction equation
[CH3:1][N:2]1[CH2:7][CH:6]([CH3:8])[C:5]([CH2:17][CH2:18][CH3:19])([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=2)[CH2:4][CH2:3]1>C(O)(=O)C>[CH3:1][N:2]1[CH2:7][CH:6]([CH3:8])[C:5]([CH2:17][CH2:18][CH3:19])([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=2)[CH:4]=[CH:3]1

Participants

3

Reactant 1

HCID 13787828HCID 13787828, compound

Product 1

HCID 12929196HCID 12929196, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Following the procedure set forth in Example 1, 43 g. of 1,5-dimethyl-4-n-propyl-4-(3-methoxyphenyl)-piperidine was reacted with 276 g. of mercuric acetate in 717 ml. of five percent aqueous acetic acid to provide, after purification by distillation, 30.2 g. of 1,5-dimethyl-4-n-propyl-4-(3-methoxyphenyl)-1,4,5,6-tetrahydropyridine. B.P. 126°-138° C. at 0.15 torr.

Workup

  1. customafter purification
  2. distillationby distillation, 30.2 g

Sources & evidence

ORD record
ord-f171af3d40574abbb984b772a49f65c1
Source dataset
uspto-grants-1981_08
Patent number
US04284635

Reaction notes

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