HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 1-(2-Cyclooctenylmethyl)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | 2-Cyclooctenylmethyl bromide | HCID 53791537 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-(2-Cyclooctenylmethyl)imidazole | HCID 54475103 | — |
Reaction Steps
2-Cyclooctenylmethyl bromide (0.7 g; 0.0035 mole) as just made was added dropwise to a refluxing solution of imidazole (0.24 g; 0.0025 mole) and potassium tertiary butoxide (0.39 g; 0.0035 mole) in dry butanol under nitrogen. After addition the mixture was stirred under reflux for 1 hour. Pure product was obtained as described in Example 4, b.p. 108°-110°/0.02 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04284641 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-14f95f94656343e9bc04b9fd24578aa9 |
| Source note | uspto-grants-1981_08 |