Hydrochloric Acid → HCID 12926017, compound

Participants

Reaction Steps

A 10% aqueous solution of sodium hydroxide was added to 4-acetoxyspiro[benzo[b]furan-2(3H),1'-cyclopropane]-3-one and the mixture was stirred at room temperature. The reaction mixture was made acidic with hydrochloric acid and extracted with ethyl acetate. The extract was washed with water, dried and distilled to remove the solvent. The residue was recrystallized from petroleum ether. By the above procedure there was obtained 4-hydroxyspiro[benzo[b]furan-2(3H),1'-cyclopropane]-3-one as yellow needles, m.p. 100°-109° C.

Provenance & Evidence