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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 89465Generated: October 27, 2026

Methanol → 4-Hydroxy-6-oxo-3-{2'-[({2-[4-(trifluoromethyl)phenyl]ethyl}amino)methyl]-1,1'-biphenyl-4-yl}-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile

https://huagongshe.com/reaction/89465

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantDichloromethaneHCID 6344—
Reactant2-[4-(Trifluoromethyl)phenyl]ethan-1-amineHCID 1988106—
Reactant3-(2'-Formyl-1,1'-biphenyl-4-yl)-4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrileHCID 54689942—
Product4-Hydroxy-6-oxo-3-{2'-[({2-[4-(trifluoromethyl)phenyl]ethyl}amino)methyl]-1,1'-biphenyl-4-yl}-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrileHCID 54678056—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-048d8362e93c4f21bd52df40245bd5e7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)