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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 894805Generated: October 30, 2026

Hydrochloric Acid → HCID 131712347, compound

https://huagongshe.com/reaction/894805

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 131712346HCID 131712346—
SolventMethanolHCID 887—
ProductHCID 131712347HCID 131712347187.2%

Reaction Steps

7-[2-(2-Formamidothiazol-4-yl)-2-(2-tert-butoxycarbonylaminoethoxyimino)acetamido]-3-chloro-3-cephem-4-carboxylic acid (syn isomer, 1.3 g.), conc.hydrochloric acid (1.2 g.) and methanol (20 ml.) were treated in similar manner to that of Example 11(3) to give 7-[2-(2-aminothiazol-4-yl)-2-(2-aminoethoxyimino)acetamido]-3-chloro-3-cephem-4-carboxylic acid dihydrochloride (syn isomer, 1.1 g.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04284631
Source datasetuspto-grants-1981_08
ORD IDord-d39de8e9183043c8957f600d009debb7
Source noteuspto-grants-1981_08