Trifluoroacetic acid → HCID 178512943, compound

Participants

Reaction Steps

From compound 8, in a manner similar to the synthesis of compound 2 (except that instead of trifluoroacetic acid use is made of its mixture with methylene chloride in the volume ratio of (1:1) α-benzyloxycarbonyl, ε-(nitroarginyl)lysylnitroarginylproline trifluoroacetate (compound 9) is obtained. The yield is 96%. αD20 =-12.0° (c=1, dimethylformamide). Ehis =0.52 (1 N acetic acid), Rf ==0.16 (B), 0.52 (C), 0.54 (D).

Provenance & Evidence