Benzene → 3-(Chlorocarbonyl)-4-oxo-4H-1-benzopyran-6,7-diyl diacetate

Participants

Reaction Steps

A mixture of 6,7-diacetoxychromone-3-carboxylic acid (18.4 g, 60 mmol), benzene (450 ml), thionyl chloride (8.6 g, 72 mmol) and N,N-dimethylformamide (3 ml) was refluxed for one hour and cooled to room temperature. After the addition of n-hexane (300 ml), the resulting precipitate was filtered off to give the desired compound (17.6 g).

Provenance & Evidence