反应详情

A mixture of 16.5 g. (0.1 mol.) of methyl carboxymethyldithiocarbamate and 14.3 g. (0.22 mol.) of sodium azide in 150 ml. of water was heated at 56° for 12 hours. The reaction mixture was extracted with ether, then acidified to pH 1.5 with dilute hydrochloric acid and extracted with ethyl acetate. The extract was dried (MgSO4) and evaporated to dryness to give 1-carboxymethyltetrazole-5-thiol, m.p. 178°-179°.

1. additionA mixture of 16.5 g
2. extractionThe reaction mixture was extracted with ether
3. extractionextracted with ethyl acetate
4. dry with materialThe extract was dried (MgSO4)
5. customevaporated to dryness