HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triisopropyl borate → (4-Methoxy-2-methylphenyl)boronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triisopropyl borate | HCID 21531 | — |
| Reactant | 1-Bromo-4-methoxy-2-methylbenzene | HCID 117915 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | (4-Methoxy-2-methylphenyl)boronic acid | HCID 2773486 | — |
Reaction Steps
The title compound was prepared by reacting 4-bromo-3-methylanisole (10 g, 0.050 mol) with n-butyl lithium (24 mL of 2.5 M solution in hexane, 0.055 mol) followed by triisopropyl borate (57.7 mL, 47.02 g, 0.25 mol) according to method F to yield 5.7 g (69%) of a white solid: MS (ESI) m/z 313 (2M−H2O—H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06914074B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-b88040ea8e29420dbfee7cd5ba11aeec |
| Source note | uspto-grants-2005_07 |