HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → 8-Fluoronaphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 1-fluoro-7-methoxynaphthalene | HCID 11148032 | — |
| Product | 8-Fluoronaphthalen-2-ol | HCID 12791513 | — |
Reaction Steps
The title compound was prepared by reacting 1-fluoro-7-methoxynaphthalene (7.99 g, 45.34 mmol) with boron tribromide (68 mL of 1 N solution, 68 mmol) according to method D to yield 3.99 g (54%) of a red solid. An analytical sample was prepared by preparative reverse phase HPLC to yield a white solid: mp 89-92° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06914074B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-53d9d9acfe6b4e1bad49cf05f294e4c3 |
| Source note | uspto-grants-2005_07 |