Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 895284Generated: October 30, 2026

3-Methoxybenzaldehyde → 5-Chloro-2-methylthio-N-[2-amino-1-{3-methoxyphenyl}-2-oxoethyl]-N-(4-methylbenzyl)pyrimidine-4-carboxamide

https://huagongshe.com/reaction/895284

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxybenzaldehydeHCID 11569—
Reactant5-Chloro-2-methylthio-N-[2-amino-1-{1,4-benzodioxan-6-yl}-2-oxoethyl]-N-(4-methylbenzyl)pyrimidine-4-carboxamideHCID 10006116—
Product5-Chloro-2-methylthio-N-[2-amino-1-{3-methoxyphenyl}-2-oxoethyl]-N-(4-methylbenzyl)pyrimidine-4-carboxamideHCID 22386185—

Reaction Steps

This was prepared in the same manner as the product from example 242, using 3-methoxybenzaldehyde as the aldehyde component, to return the title compound as a solid, 1.74 g, (76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06914160B1
Source datasetuspto-grants-2005_07
ORD IDord-62a25349603345e39939956cea943489
Source noteuspto-grants-2005_07