Ammonia → HCID 22386195, compound

HRID 895285Notes

Reaction equation

HRID 895285 reaction equation
[Cl:1][C:2]1[C:3]([C:12]([N:14]([CH:23]([C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([O:33][CH3:34])[CH:28]=2)[C:24]([NH2:26])=[O:25])[CH2:15][C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)=[O:13])=[N:4][C:5](S(C)(=O)=O)=[N:6][CH:7]=1.[NH3:35]>>[Cl:1][C:2]1[C:3]([C:12]([N:14]([CH:23]([C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([O:33][CH3:34])[CH:28]=2)[C:24]([NH2:26])=[O:25])[CH2:15][C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)=[O:13])=[N:4][C:5]([NH2:35])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22386187HCID 22386187, compound

Product 1

HCID 22386195HCID 22386195, compound

Procedure

The title compound was prepared from the sulfone of example 248, using the method from example 244 and ammonia as the amine, to return the title compound as a foam, 22 mg, (12%)

Sources & evidence

ORD record
ord-86b55c5c9bbc4613993875357f2d7729
Source dataset
uspto-grants-2005_07
Patent number
US06914160B1

Reaction notes

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