HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzaldehyde → 5-Methyl-2-methylthio-N-[2-amino-1-{3-methoxyphenyl}-2-oxoethyl]-N-(4-methylbenzyl)pyrimidine-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzaldehyde | HCID 11569 | — |
| Reactant | 5-Chloro-2-methylthio-N-[2-amino-1-{1,4-benzodioxan-6-yl}-2-oxoethyl]-N-(4-methylbenzyl)pyrimidine-4-carboxamide | HCID 10006116 | — |
| Reactant | HCID 178432746 | HCID 178432746 | — |
| Product | 5-Methyl-2-methylthio-N-[2-amino-1-{3-methoxyphenyl}-2-oxoethyl]-N-(4-methylbenzyl)pyrimidine-4-carboxamide | HCID 22386206 | — |
Reaction Steps
This was prepared in the same manner as the product from example 242 using 5-methyl-2-methylthiopyrimidine-4-carboxylic acid (preparation 17) and 3-methoxybenzaldehyde as the acid and aldehyde components to give the title compound as a solid, 0.97 g, (72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06914160B1 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-d0e7ce75b7024ca0a12c8dc4683f2756 |
| Source note | uspto-grants-2005_07 |