Morpholine → 4-(6-Methoxy-3-nitropyrid-2-yl)morpholine

HRID 895303Notes

Reaction equation

HRID 895303 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([O:11][CH3:12])[N:3]=1.[NH:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>C(O)C>[CH3:12][O:11][C:4]1[N:3]=[C:2]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 8083MorpholineHCID 27950292-Chloro-6-methoxy-3-nitropyridine

Product 1

HCID 28264174-(6-Methoxy-3-nitropyrid-2-yl)morpholine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

5 g (0.0265 mol) of the product 2-chloro-3-nitro-6-methoxypyridine, 50 ml of ethanol and 4.62 ml (0.053 mol) of morpholine were placed in a fully equipped round-bottomed flask.

Sources & evidence

ORD record
ord-642b2278da7540529ff1cb395433d72e
Source dataset
uspto-grants-2005_07
Patent number
US06916345B2

Reaction notes

Loading…