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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 895320Generated: October 29, 2026

N-(2-Hydroxyethyl)aniline → HCID 86585179, compound

https://huagongshe.com/reaction/895320

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-Hydroxyethyl)anilineHCID 31235—
ReactantHCID 12477186HCID 12477186—
SolventEthanolHCID 702—
ProductHCID 86585179HCID 8658517976%

Reaction Conditions

Temperature80 °C

Reaction Steps

0.283 g of 3-(2-phenyl-2-chloro acetyl) N-methylindole (1 mmole) (H. Nakamura and T. Goto, Heterocyles, 10, 167-170 (1978) and 0.274 g of 2-anilino ethanol (2.0 mmole) were dissolved in 3 ml of dry ethanol and heated in a sealed tube at 80° C. for 8 hours. On cooling the product crystallized out as pale yellow needles which was filtered and dried to yield 0.21 g of N-phenyl indole oxazine Compound 17.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06916667B2
Source datasetuspto-grants-2005_07
ORD IDord-6066b22814e147499bb0dddbb188b256
Source noteuspto-grants-2005_07